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Deliberately breaking with the classical biology-centered description of marine organisms and their products, Marine Microbiology emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues.
Following a definition of the field, Marine Microbiology goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed.
A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.
PART I: INTRODUCTION AND PROSPECTS
- Marine microorganisms and their bioactive compounds
- Characterization of marine microorganisms
- Sampling and isolation techniques in marine microbiology
PART II: SOURCES OF BIOACTIVE COMPOUNDS
- Sources and isolation aspects of marine biomaterials
- Fungal bioactive gene clusters
- Treasure-hunting of marine microorganisms from the deep sea
- Marine cyanobacteria: a prolific source of bioactive pharmaceutical agents
- Marine actinomycetes as source of pharmaceutically important compounds
- Marine symbiotic microorganisms: new dimensions in natural products research
- Bioprospecting of marine microbial symbionts
- Sponges: a reservoirfor microorganisms-derived bioactive metabolites
- Marine viruses: an approach to global ecosystems
PART III: BIOLOGICAL ACTIVITIES OF MARINE NATURAL COMPOUNDS
- Natural compounds of marine microorganisms and their biological activities
- Bioactive compounds from marine actinomycetes
- Anticancer potentials of marine-derived fungal metabolites
- Antimicrobial activity of the marine-derived fatty acid eicosapentaenoic acid (C20:5n-3)
- Antifungal and antimycotoxin activities of marine microbes and their compounds
- Marine fungi as potential pharmaceutical and cosmeceutical agents
- The role of microbial siderophores in algal-bacterial symbioses
PART IV: BIOMEDICAL, PHARMACEUTICAL AND BIOCHEMICAL APPLICATIONS
- Harnessing the chemical and genetic diversity of marine organisms for medical applications
- Biomedical applications of mycosporine-like amino acids
- Anti-tuberculosis materials from marine microbes
- Antimicrobial agents from marine cyanobacteria and actinomycetes
- Cathepsin B inhibitors from marine Pseudomonas species
- Application of enzymes derived from marine microbes
- Marine microbial enzymes: biotechnological and biomedical aspects
- Marine biocatalysts for reactions in organic chemistry
- Chitin and chitosan from microorganisms
PART V: APPLICATIONS IN FOOD AND AQUACULTURE
- Production and functional food application of microbes-derived compounds
- Marine bacteria as probiotics and their applications in aquaculture
- Application of probiotics and prebiotics for sustainable marine aquaculture development
- Marine bacteriophages in the biocontrol of fish and shellfish diseases
Se-Kwon Kim is Professor of Marine Biochemistry at Pukyong National University in Busan, South Korea. A graduate of PKNU, he conducted his postdoctoral studies at the University of Illinois (USA), and was a visiting scientist at the Memorial University of Newfoundland (Canada). His major research interests are the investigation and development of bioactive substances derived from marine organisms and their application as cosmeceuticals and nutraceuticals. Professor Kim is the current editor-in-chief of the Korean Journal of Marine Bioscience and Biotechnology. He has authored over 450 research papers, holds 72 patents, and has written or edited more than 30 books.
