Population genomics is a rapidly emerging field that has the potential to transform our understanding of how evolutionary forces shape genomic diversity among microbes. There have already been considerable advances in understanding gene flow and spread of adaptive traits, and in linking epidemiology with evolutionary biology. The current challenge is to find unifying evolutionary principles for organisms that display a wide range of reproductive biology – from highly clonal to promiscuous – and for which the vast majority have eluded cultivation. This requires interdisciplinary approaches that incorporate novel computational tools, testing of existing and novel population genetic models, and creative new ways of linking genetic diversity to ecological factors. This pioneering book will discuss the advances made and promises of population genomics in microorganisms, outlining some of the key theoretical and practical challenges for microbial population genomics, including defining and identifying populations, genomics-based reverse ecology and building appropriate tools to understand microbes in a variety of complex environments.
Preface
I. Concepts and perspectives
1. Microbial Population Genomics Perspectives and Promises / Martin Polz, MIT, Om Rajora, Umiversity of New Brunswick
2. Population Genomics and Microbial Species Concept / Jesse Shapiro, University of Montreal
3. Population Genomics and Metagenomics / Jill Banfield, University of California Berkeley, Vincent Denef, University of Michigan
4. Reverse Ecology / Martin Polz, MIT
5. Genomic and Computational Methods in Microbial Population Genomics / Xavier Didelot, Imperial College, Daniel Falush, Swansea University, Eric Alm, MIT
II. Population Genomics of Bacteria
6. Population Genomics of Plant Pathogenic Bacteria / David Guttman, University of Toronto, Boris Vinatzer, Virginia Tech
7. Population Genomics of Human Pathogenic Bacteria / Bill Hanage, Harvard School of Public Health, Ed Feil, University of Bath, Nick Croucher, Imperial College
8. Population Genomics of Symbiotic Bacteria / Nancy Moran, University of Texas, Austin
9. Population Genomics of Dairy Industrial Bacteria / Paul W. O'Toole, University College, Cork, Paola Cremonesi, NRC, Italy
10. Population Genomics of Environmental Bacteria and Archaea / Rachel Whitaker, University of Illinois, Urbana-Champaign, Daniel Buckley, Cornell University, Thane Papke, University of Connecticut, Francisco Rodriguez-Valera, University Miguel Hernandez
III. Population Genomics of Fungi
11. Population Genomics of Plant Pathogenic Fungi / Michael G. Milgroom, Cornell University
12. Population Genomics of Human Pathogenic Fungi / Bruce McDonald, ETH Zurich Institute of Integrative Biology
13. Population Genomics and Yeast Biodiversity and Evolution / Cletus P Kurtzman, USDA ARS, Gianni Liti, Institute of Genetics, University of Nottingham, Mathew R. Goddard, University of Auckland, University of Lincoln
14. Population Genomics of Domestication in Yeast / Edward J. Louis, Institute of Genetics, University of Nottingham, Jose Paulo Sampaio, Universidade Nova de Lisboa, Caparica, Portugal
IV. Population Genomics of Viruses
15. Population Genomics of Human Viruses / Richard A. Neher, Max Planck Institute of Developmental Biology, Francois Balloux, University of Cambridge
16. Population Genomics of Plant Viruses / Zhongguo Xiong, University of Arizona, H.C. Prasanna, Indian Institute of Vegetable Research
17. Population Genomics of Bacterial Viruses / Mathew Sullivan, University of Ohio
18. Population Genomics of Insect Viruses / Robert S. Cornman, Bee Research Lab, USDA-ARS, Clement Gilbert, Universite de Poitiers
Index