Genetics: A Molecular Perspective

About this book

For courses in genetics in departments of biology, genetics, and agriculture. Covers DNA through to genetic expression at the modular level. Emphasizes principles rather than details. Interactive tutorials and excercises available on the Companion Website.

Contents

I. DNA-THE CHEMICAL BASIS OF GENETICS. 1. Introduction. 2. DNA Structure and Analysis. 3. DNA Replication and Recombination. 4. Chromosome Structure and DNA Sequence Organization. II. EXPRESSION OF GENETIC INFORMATION. 5. The Genetic Code and Transcription. 6. Translation and Proteins. 7. Gene Mutation, DNA Repair, and Transposable Elements. III. TRANSMISSION OF GENETIC INFORMATION. 8. Mitosis and Meiosis. 9. Mendelian Genetics. 10. Extensions of Mendelian Genetics. 11. Sex Chromosomes and Sex Determination. 12. Linkage, Crossing over, and Mapping in Eukaryotes. 13. Chromosome Mutations: Variations in Number and Arrangement. 14. Extranuclear Inheritance. IV. DNA BIOTECHNOLOGY AND GENETIC ANALYSIS. 15. Genetics of Bacteria and Bacteriophages. 16. Recombinant DNA Technology. 17. Genomics, Bioinformatics, and Proteomics. 18. Applications and Ethics of Genetic Technology. V. REGULATION OF GENE EXPRESSION. 19. Gene Regulation in Prokaryotes. 20. Gene Regulation in Eukaryotes. VI. ADVANCED TOPICS IN EUKARYOTIC GENETICS. 21. Developmental Genetics. 22. Genetics and Cancer. 23. Chromosome Genetics: Immunoglobulins, Isochores, and Chromatid Dynamics. VII. GENES AND POPULATIONS. 24. Quantitative Genetics. 25. Population Genetics. 26. Genetics and Evolution. 27. Conservation Genetics.

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Biography

William S. Klug is currently Professor of Biology at The College of New Jersey (formerly Trenton State College) in Ewing, New Jersey. He served as Chairman of the Biology Department for 17 years, a position to which he was first elected in 1974. He received his B.A. degree in Biology from Wabash College in Crawfordsville, Indiana and his Ph.D. from Northwestern University in Evanston, Illinois. Prior to coming to Trenton State College, he returned to Wabash College as an Assistant Professor, where he first taught genetics as well as general biology and electron microscopy. His research interests have involved ultrastructural and molecular genetic studies of oogenesis in Drosophila. He has taught the genetics course as well as the senior capstone seminar course in human and molecular genetics to undergraduate Biology majors for each of the last 33 years. He was the recent recipient of the first annual teaching award given at The College of New Jersey as the faculty member who most challenges students to meet high standards. Michael R. Cummings is currently Associate Professor in the Department of Biological Sciences and in the Department of Molecular Genetics at the University of Illinois at Chicago. He has also served on the faculty at Northwestern University and Florida State University. He received his B.A. from St. Mary's College in Winona, Minnesota, and his M.S. and Ph.D. from Northwestern University in Evanston, Illinois. He has also written textbooks in human genetics and general biology for non-majors. His research interests center on the molecular organization and physical mapping of human acrocentric chromosomes. At the undergraduate level, he teaches courses in Mendelian genetics, human genetics, and general biology for non-majors. He has received numerous teaching awards given by the university and by student organizations.