This volume combines reliable RNAi protocols for a variety of species with discussion of strategies for the effective design of experiments using this important new technique that is changing the way experimental science is done.
"Because of the overwhelming plethora of studies, this book, written by leaders in the field, arrives as a welcome road map for beginners and experts alike. The volume provides a broad overview of the basic mechanisms and applications of RNAi to different model organisms for functional gene analysis, including nonclassical model systems such as the parasitic protozoan Trypanosoma brucei and the chicken embryo. In addition, several chapters are devoted to subjects that are more loosely related to RNAi and thus less frequently reviewed in papers in the field....RNAi is indeed obligatory reading for anyone interested in modern molecular biology" Science