Updated to incorporate the many advances in genomics, protein engineering, computational biology and bioinformatics.
Genes, genetic codes, and mutation; dynamics of genes in populations; evolutionary change in nucleotide sequences; rates and patterns of nucleotide substitution; molecular phylogenetics; gene duplication, exon shuffling, and concerted evolution; evolution by transposition; genome evolution. Appendices: timetables of evolution; basics of probability. Literature cited.