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About this book
Assuming only a basic knowledge of molecular biology, this is the fourth in a series of manuals which explains how to clone, manipulate, analyze and sequence large segments of DNA, and relate expressed sequence to phenotypic variation. The techniques are written for application to animal DNA as well as human genomes. They deal plainly with sources of failure, and solutions.
Contents
Meiotic mapping in humans; genetic and comparative mapping in mice; identification and analysis of DNA polymorphisms; DNA markers for physical mapping; representational difference analysis; somatic cell genetics and radiation hybrid mapping; flouresence in situ hybridization.
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