Mutation: The History of an Idea from Darwin to Genomics

About this book

This work, by noted author Elof A. Carlson, explores six generations of mutation research, providing the background--the people and the ideas--for this biological journey. The book shows how generational definitions or assessments of mutation have responded to the technologies added to science and the experiments that abounded with the inquiries of each successive generation. These observations are combined with an exploration of how the nonscientific public has shifted its understanding and concern about mutations over the past 150 or more years. Carlson's historical approach in this book--examining the evolution of a concept--reveals the way science works, incrementally by small steps of additions and replacements rather than by dramatic, and rare, paradigm shifts.

Contents

Preface
1. A Brief Overview of the Concept of Mutation
2. Ideas of Mutation before There Was a Mendelian Basis for Genetics
3. Cytological and Mendelian Aspects of Mutation
4. The Fly Lab Redefines Mutation
5. Radiation and the Analysis of Mutation by Mutagenesis
6. Using Biochemical Approaches to Study Mutation
7. Mutation in Relation to Gene Structure
8. Mutation in Relation to Evolution
9. Mutation in Relation to Genetic Engineering
10. Mutation in Relation to Society
11. Mutation in Relation to History and Philosophy of Science
Glossary of Terms Associated with Mutation
Index

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